Combined use of radioiodine therapy and radiofrequency ablation in treating postsurgical thyroid remnant of differentiated thyroid carcinoma

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Radioiodine-remnant ablation in low-risk differentiated thyroid cancer: pros.

Differentiated thyroid carcinomas are typically treated with total thyroidectomy as initial therapy. Subsequent radioactive iodine (RAI) ablation destroys post-surgical thyroid remnants, can additionally provide adjuvant therapy of residual and metastatic thyroid cancers, and enhances the sensitivity and specificity of further diagnostic studies. There is current controversy regarding whether a...

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Differentiated thyroid carcinoma referred for radioiodine therapy.

OBJECTIVE The current work was conducted to study the disease status and treatment results of patients with differentiated thyroid carcinoma referred for radioactive iodine therapy. METHODS Retrospective review of 78 patients with differentiated thyroid carcinoma referred for radioiodine therapy in the Nuclear Medicine Unit, King Abdulaziz Hospital and Oncology Center, Jeddah, Kingdom of Saud...

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Recombinant human thyroid-stimulating hormone in radioiodine thyroid remnant ablation.

BACKGROUND To prevent the unwarranted effects of post-thyroidectomy hypothyroidism prior to radiodine (RAI) ablation, patients with well-differentiated thyroid cancer can currently undergo this treatment while in a euthyroid state. This is achieved with the use of recombinant human thyroid-stimulating hormone (rhTSH) injections prior to the ablation. OBJECTIVES To demonstrate the efficacy of ...

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Preablation Imaging Before Radioiodine Ablation in Differentiated Thyroid Carcinoma

Detection of residual tissue after thyroidectomy for papillary or follicular thyroid carcinoma may be performed using diagnostic imaging with either 123I or 131I. The former is often preferred to avoid ‘‘stunning’’—defined as a reduction in uptake of the therapeutic dose of 131I caused by some form of cell damage from the diagnostic dosage of the radionuclide. Stunning could potentially reduce ...

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Adjuvant thyroid remnant ablation in patients with differentiated thyroid carcinoma confined to the thyroid: a comparison of ablation success with different activities of radioiodine (I-131).

OBJECTIVE To assess efficiency of various I-131 activities on thyroid remnant ablation in thyroid cancer patients. The significance of patients' characteristics, pathologic features and levels of Tg were analyzed. PATIENTS AND METHODS This study included 259 consecutive differentiated thyroid cancer patients, with disease confined to the thyroid, treated with I-131 after total thyroidectomy. ...

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ژورنال

عنوان ژورنال: Journal of Cancer Research and Therapeutics

سال: 2015

ISSN: 0973-1482

DOI: 10.4103/0973-1482.170530